[Chopsticks]

I don't see any problem with an anime running for hundreds of episodes as long as you continue to have good story lines.
I never really liked One Piece to begin with, but prime examples are Naruto and Bleach (not counting the filler).
I honestly think that if InuYasha were compressed into one of those 26 episode series, it would actually be a lot better. The story isn't that bad, it's just ONE HUUNNNDREEDD AND SIIXXXTTYYY SEEVVEENN EPPIISSOODDEEES isn't very appropriate.