I've got different ways to deal with them:
Trash compactor
Huge laser
Barbara Stresand Laser Disk
The Force
Healing Spells
The Holy Grenade (aaaaaaalleluia.....)
Daemonhammer (see Warhammer 40k) or 'Godsplitter'
Blackhole
Replicants (see Stargate SG-1), organics are no match for nanotech.
An army of Worms with bazookas
And finally an Hadoken.
I wonder what HK-47 would say about them (dead meatbags?)
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