[qzar9999]

Red really knocked it out of the park with Office Politics. I think it'll never be topped until and unless he comes back to us.

To answer the original topic -
Our subject gets dosed/spelled/whatever by accident, or somehow by her own fault.
There's a nice, slow, really subtle shrink to start things off. She doesn't even realize anything is happening.
Maybe she feels an unexplained tingle, or shiver.
She fidgets with her loose clothing, trying to adjust the fit.
She notices something is wrong, but either can't put her finger on it or is in denial.
Her clothes slip again. Maybe threatening (or going ahead with!) a nip slip.
Her pants/skirt/whatever slides off her hips.
Her panties hang on, shifting down to show a peek of her ass, and then they hit the floor too.
She realizes exactly what's happening. Panics.
Her shirt gets bigger, her bra sliding off her breasts underneath it.
She struggles desperately to keep her huge top on, but it's a losing battle.
She freaks out more watching everything grow around her.
She talks to herself: This is impossible! Oh shit, I'm still shrinking! My clothes are falling off of me! How small am I gonna get? Etc etc etc
The top and bra become unmanageable, and she's left defeated and nude, knee-deep in her oversized clothing.
She covers herself with her hands, embarrassment joining her panic.
When she gets to around half her size, maybe a bit smaller, she starts to feel something else: arousal. She doesn't really want it, can't control it, knows she should stay focused on figuring out her situation...but the turn-on is part of what's happening to her, and it's only getting stronger as she gets smaller.
She continues to try to control herself, slowly losing the battle as she gets tinier and hornier.
She finally collapses into self-pleasuring ecstasy, writhing around in her gigantic outfit.
She knows she's still shrinking, but now she's too horny to care.
She orgasms right about the time she stops shrinking.
Exhausted, maybe starting to feel her panic or embarrassment returning, she crawls out of her outfit, stupefied at what's become of her.

A sequence that goes like this would hit so many notes for me that if there's ever a live-action video that incorporates them all with competent effects and an half-decent actress I'll be walking funny for hours afterwards. You may notice that Office Politics ticks many of those boxes, in fact, though not quite all of them. And anyone who's ready my stories may detect a familiar pattern. Lol