https://gamejolt.com/games/ShrinkingViolet/257266
Just found this indie game on Gamejolt. It's a point-and-click adventure game about the titular Violet trying to save five people who were accidentally shrunk in a basement lab. Violet can shrink and grow at will using a remote control, and changing size figures heavily into the puzzles. Two of the people she's trying to rescue are female as well